Medicine is full of them - some are easy, like starting a family. Some are harder - do I choose medicine versus surgery for this problem?
Some are heartbreakingly awful. Any choice leads to a bad outcome. Allowing your seriously ill teen to enter hospice. Organ donation. Every clinical field can give examples, they're just more common in some like geriatrics and palliative medicine.
We don't have many, but the ones we have are big ones. And we just have to remember not to judge, for we have been lucky enough to live our lives not to have to make those decisions. Yet.